2,6-Di-tert-butylphenol → HCID 14368273、化合物
反応式
[Cl:1][C:2]1[N:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].[C:12]([C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([C:22]([CH3:25])([CH3:24])[CH3:23])[C:17]=1[OH:26])([CH3:15])([CH3:14])[CH3:13]>>[Cl:1][C:2]1[N:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[C:4]([C:20]1[CH:19]=[C:18]([C:22]([CH3:23])([CH3:24])[CH3:25])[C:17]([OH:26])=[C:16]([C:12]([CH3:15])([CH3:14])[CH3:13])[CH:21]=1)=[O:5]参加物
3
実験手順
The similar procedure in reference example 1 by using 19 g of 2-chloro-6-methylnicotinoyl chloride, 24.7 g of 2,6-di-tertiary butylphenol and 31.3 g of anhydrous stannic chloride is performed and the obtained crude product is recrystallized from hexane to give 29.8 g of 4-(2-chloro-6-methylnicotinoyl)-2,6-di-tertiary butylphenol as pale yellow crystals, melting at 116°-117° C.
後処理
- customthe obtained crude product
- customis recrystallized from hexane