Water → 5-(Ethanesulfonyl)-1,3-benzothiazol-2-amine
反応式
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:13]([O-])=O.[NH2:16][C:17](N)=[S:18].O>S1(CCCC1)(=O)=O>[NH2:16][C:17]1[S:18][C:2]2[CH:7]=[CH:6][C:5]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])=[CH:4][C:3]=2[N:13]=1参加物
5
反応条件
- 温度
- 120 °C
実験手順
A suspension of 12.8 g of ethyl 4-chloro-3-nitrophenyl sulphone and 15.2 g of thiourea in 50 ml of sulpholane is heated to 120° C. and this temperature is maintained for 1.5 hours. The mixture is discharged into 600 ml of water, and the solid is filtered off with suction and washed with water. 10.6 g of colourless 2-amino-5-ethanesulphonylbenzothiazole are obtained.
後処理
- temperaturethis temperature is maintained for 1.5 hours
- filtrationthe solid is filtered off with suction
- washwashed with water
出典と根拠
- ORDレコード
- ord-e308b529ecba4678aba7c09a10c6a3eb
- 出典データセット
- uspto-grants-1989_02
- 特許番号
- US04808723
反応ノート
読み込み中…