Potassium Carbonate → 223104-08-3

HRID 1383280ノート

反応式

HRID 1383280 の反応式
C(=O)([O-])[O-].[K+].[K+].Br[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]/[CH:17]=[CH:18]\[CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24]>CN1CCCC1=O>[O:24]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH:17]=[CH:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]1=[O:25]

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 86757096HCID 86757096、化合物

生成物 1

HCID 6515677223104-08-3収率 53%

試薬・触媒・溶媒 1

HCID 13387N-methyl-2-pyrrolidone溶媒2 回

反応条件

温度
112.5 °C

実験手順

25 g of potassium carbonate were suspended in 300 ml of N-methyl pyrrolidone. 30 g (0.09 mol) of crude 6Z-16-bromohexadec-6-enoic acid in 200 ml of N-methyl- pyrrolidone were added dropwise while stirring at 110-115° C. within 10 hours. After usual work up 18 g of crude product were obtained, and after chromatography 12 g (53%) of Z-oxacycloheptadec-7-en-2-one were obtained having the following characteristics: Z/E=93/7;

後処理

  1. customAfter usual work up 18 g of crude product were obtained

出典と根拠

ORDレコード
ord-dcf6d2501f0e499ab4b2d2766d1e0ee5
出典データセット
uspto-grants-2001_07
特許番号
US06255276B1

反応ノート

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