Hydrochloric Acid → HCID 21187705、化合物

反応式

[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([OH:18])[CH2:17][CH2:16][C:11]2([O:15]CCO2)[CH2:10][CH2:9]1.Cl.C(=O)(O)[O-].[Na+]>O1CCOCC1>[CH2:8]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1([OH:18])[CH2:9][CH2:10][C:11](=[O:15])[CH2:16][CH2:17]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:2]=1

参加物

実験手順

To a solution of of 8-(2-Hydroxy-phenyl)-1,4-dioxa-spiro[4.5]decan-8-ol (2.76 g, 8.12 mmol) in 70 mL 1,4-dioxane was added aqueous hydrogen chloride (40.6 mL 1M, 40.6 mmol). The solution was stirred for 30 min., poured onto saturated sodium bicarbonate, and extracted with ethylacetate. The combined organic layers were washed with saturated sodium chloride, dried with magnesium sulfate, and concentrated in vacuo to give the product (1.96 g, 82%).