Hydrochloric Acid → 2,3-Diaminophenol--hydrogen chloride (1/2)

HRID 1384001ノート

反応式

HRID 1384001 の反応式
[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9].[ClH:10]>C(O)C>[ClH:10].[ClH:10].[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 5799372,3-Diaminophenol

生成物 1

HCID 184017512,3-Diaminophenol--hydrogen chloride (1/2)

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
50 °C

実験手順

In a 250 ml single neck round bottom flask was added 2,3-diaminophenol (10 g, 80.55 mmol) to ethanol (100 ml). This mixture was heated to 50° C. to achieve dissolution. The resulting solution is cooled to −5 to 0° C. and an excess of anhydrous hydrogen chloride gas was added to form a viscous slurry. The resulting mixture was stirred for two hours at ˜0° C., then filtered, and rinsed with chilled methanol (30 ml). The solvents were removed in vacuo and the residue was dried overnight.

後処理

  1. dissolutiondissolution
  2. temperatureThe resulting solution is cooled to −5 to 0° C.
  3. customto form a viscous slurry
  4. filtrationfiltered
  5. washrinsed with chilled methanol (30 ml)
  6. customThe solvents were removed in vacuo
  7. customthe residue was dried overnight

出典と根拠

ORDレコード
ord-8db2d0d1e5914a8a9fe096d494e21526
出典データセット
uspto-grants-2001_07
特許番号
US06255494B1

反応ノート

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