3,4-Dichloroaniline → 7-Acetamino-1-(3,4-dichloroanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride

反応式

[NH:1]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([CH2:16][C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)=[N:10][N:11]=[C:12]2[Cl:15])=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].[Cl:23][C:24]1[CH:25]=[C:26]([CH:28]=[CH:29][C:30]=1[Cl:31])[NH2:27]>>[ClH:15].[NH:1]([C:5]1[CH:14]=[C:13]2[C:8]([C:9]([CH2:16][C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)=[N:10][N:11]=[C:12]2[NH:27][C:26]2[CH:28]=[CH:29][C:30]([Cl:31])=[C:24]([Cl:23])[CH:25]=2)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3]

参加物

反応物 2

HCID 72573,4-Dichloroaniline

HCID 227419517-Acetamino-1-chloro-4-(4-pyridylmethyl)phthalazine

生成物 1

HCID 227419777-Acetamino-1-(3,4-dichloroanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride

実験手順

The preparation is carried out in the manner described under Example 25, starting from 7-acetamino-1-chioro-4-(4-pyridylmethyl)phthalazine and 3,4-dichloroaniline.

出典と根拠

ORDレコード: ord-7072af7c091b46ab85318265f7878d0e
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06258812B1

反応ノート

読み込み中…