Aluminum(III) Chloride → HCID 21707192、化合物

HRID 1384181ノート

反応式

HRID 1384181 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[C:11]([O:13]C)[CH:12]=1)[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2.[Al+3].[Cl-].[Cl-].[Cl-]>C(Cl)Cl>[OH:13][C:11]1[CH:12]=[C:3]([O:2][CH3:1])[CH:4]=[C:5]2[C:10]=1[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2

参加物

4

反応物 2

HCID 6451240Aluminum(III) ChlorideHCID 114470756,8-dimethoxy-3,4-dihydro-2H-naphthalen-1-one

生成物 1

HCID 21707192HCID 21707192、化合物収率 98.6%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 6,8-dimethoxy-3,4-dihydro-2H-naphthalen-1-one (15 g, 72.8 mmole), prepared according to the procedure of J. Chem. Soc., London 2782 (1955), which is incorporated herein by reference, in methylene chloride (150 mL) at 0° C. was treated portionwise with AlCl3 (14.3 g, 107 mmole), stirred for 20 h at room temperature, poured onto ice with stirring and extracted with methylene chloride when the ice melted. The extracts were washed with water and brine, dried (MgSO4) and concentrated to provide 13.8 g of the title compound.

後処理

  1. additionpoured onto ice
  2. stirringwith stirring
  3. extractionextracted with methylene chloride when the ice
  4. washThe extracts were washed with water and brine
  5. dry with materialdried (MgSO4)
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-fd04c7475365431cbeed96c5a8345339
出典データセット
uspto-grants-2001_07
特許番号
US06258822B1

反応ノート

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