Aluminum isopropoxide → 3-(3-Isopropylphenyl)butanol

HRID 1384408ノート

反応式

HRID 1384408 の反応式
CC(C)[O-].[Al+3].CC(C)[O-].CC(C)[O-].[CH:14]([C:17]1[CH:18]=[C:19]([CH:23]([CH3:27])[CH2:24][CH:25]=[O:26])[CH:20]=[CH:21][CH:22]=1)([CH3:16])[CH3:15]>C(O)(C)C.CCOCC>[CH:14]([C:17]1[CH:18]=[C:19]([CH:23]([CH3:27])[CH2:24][CH2:25][OH:26])[CH:20]=[CH:21][CH:22]=1)([CH3:16])[CH3:15]

参加物

5

反応物 2

HCID 11143Aluminum isopropoxideHCID 86209Florhydral

生成物 1

HCID 220355223-(3-Isopropylphenyl)butanol収率 73.7%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 3776Isopropanol溶媒2 回

実験手順

To a refluxing solution of 132.8 g aluminum isopropoxide in 800 ml of isopropanol, a solution of 300 g of 3-(3-isopropylphenyl)butanal in 200 ml of isopropanol was dropped in. The resulting solution was refluxed for 1.5 hours, then cooled and diluted with ether. Then, the organic phase was washed with brine, dried, and evaporated to dryness. The resulting oil was distilled to yield 223.5 g of a colorless oil.

後処理

  1. temperatureThe resulting solution was refluxed for 1.5 hours
  2. temperaturecooled
  3. washThen, the organic phase was washed with brine
  4. customdried
  5. customevaporated to dryness
  6. distillationThe resulting oil was distilled

出典と根拠

ORDレコード
ord-50b35a20e7ae42c9a03a95b57838f8f4
出典データセット
uspto-grants-2001_07
特許番号
US06258854B1

反応ノート

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