2-Phenyl-2-propanol → 2-Phenylpropan-2-yl 2-bromoacetate

反応式

[C:1]1([C:7]([OH:10])([CH3:9])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:11][CH2:12][C:13](Cl)=[O:14]>>[Br:11][CH2:12][C:13]([O:10][C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)([CH3:9])[CH3:8])=[O:14]

参加物

反応物 2

HCID 120532-Phenyl-2-propanol

HCID 89602Bromoacetyl chloride

生成物 1

HCID 538027202-Phenylpropan-2-yl 2-bromoacetate

実験手順

The sub-title compound was prepared analogously to the procedure described in Example 30(i) from 2-phenyl-2-propanol (3 g; 22 mmol) and bromacetylchloride (4.16 g, 26 mmol). Yield 1.2 g (44%).

出典と根拠

ORDレコード: ord-2d103b0a311b44768d749d400f72c1e1
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06262028B1

反応ノート

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