Hydrochloric Acid → 3-(4-Bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine hydrochloride
反応式
[Br:1][C:2]1[CH:16]=[C:15]([CH3:17])[C:5]([O:6][CH2:7][CH:8]2[CH2:13][CH2:12][CH2:11][N:10]([CH3:14])[CH2:9]2)=[C:4]([CH3:18])[CH:3]=1.[ClH:19]>CCOCC>[ClH:19].[Br:1][C:2]1[CH:16]=[C:15]([CH3:17])[C:5]([O:6][CH2:7][CH:8]2[CH2:13][CH2:12][CH2:11][N:10]([CH3:14])[CH2:9]2)=[C:4]([CH3:18])[CH:3]=1参加物
4
実験手順
The 3-(4-bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine was treated with 1N hydrochloric acid in ether, and the precipitated salt was recrystallized from acetonitrile/tert-butyl methyl ether to yield 3-(4-bromo-2,6-dimethylphenoxymethyl)-1-methylpiperidine hydrochloride, m.p. 180.9-183.5° C.
後処理
- customthe precipitated salt was recrystallized from acetonitrile/tert-butyl methyl ether
出典と根拠
- ORDレコード
- ord-5a1a489dfc674342a152d07b142905e8
- 出典データセット
- uspto-grants-2001_07
- 特許番号
- US06262078B1
反応ノート
読み込み中…