2-Bromopropane → HCID 53710128、化合物

反応式

[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][NH:11]2)=[CH:7][CH:6]=1)=[O:4].Br[CH:17]([CH3:19])[CH3:18]>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][N:11]2[CH:17]([CH3:19])[CH3:18])=[CH:7][CH:6]=1)=[O:4]

参加物

反応物 2

HCID 63582-Bromopropane

HCID 178438014HCID 178438014、化合物

生成物 1

HCID 53710128HCID 53710128、化合物収率 40%

実験手順

This compound was prepared according to the method of Preparation 3, using 750 mg (3.67 mmol, 1.0 equiv) 3-ethyl-1H-indazole-6-carboxylic acid methyl ester and 0.38 mL (4.04 mmol, 1.1 equiv) 2-bromopropane as starting materials to give 359 mg (40%) of a clear oil: HRMS calcd for C14H18N2O2+H: 247.1448. Found: 247.14530.

後処理

customThis compound was prepared
customaccording to the method of Preparation 3

出典と根拠

ORDレコード: ord-56cbee09e91d48b99252c0fc270f9f60
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06262040B1

反応ノート

読み込み中…

参加物