2-methylpropyl (2S)-2-aminopropanoate → N-[(6methoxybenzothiophen-2-yl)acetyl]alanine iso-butyl ester
反応式
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:6]2[CH:7]=[C:8]([CH2:10][C:11]([OH:13])=O)[S:9][C:5]=2[CH:4]=1.[CH2:16]([O:20][C:21](=[O:25])[C@H:22]([CH3:24])[NH2:23])[CH:17]([CH3:19])[CH3:18]>>[CH2:16]([O:20][C:21](=[O:25])[C@H:22]([CH3:24])[NH:23][C:11](=[O:13])[CH2:10][C:8]1[S:9][C:5]2[CH:4]=[C:3]([O:2][CH3:1])[CH:15]=[CH:14][C:6]=2[CH:7]=1)[CH:17]([CH3:19])[CH3:18]参加物
3
実験手順
Following General Procedure I′ above, and using (6-methoxybenzothiophen-2-yl)acetic acid and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
後処理
- customprepared
出典と根拠
- ORDレコード
- ord-da2ad5369c31463daa41ab832e48ffd8