化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl 2-(4-bromo-2-nitrophenyl)acetate → 6-bromo-2,3-dihydro-1H-indol-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-(4-bromo-2-nitrophenyl)acetate | HCID 23247724 | — |
| 触媒 | Iron | HCID 23925 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 6-bromo-2,3-dihydro-1H-indol-2-one | HCID 2773289 | 43% |
反応手順
Using a procedure analogous to that described for the starting material in Example 57, ethyl(4-bromo-2-nitrophenyl)acetate (26 g, 90 mmol) was treated with iron in acetic acid. The product thus obtained was recystallised from ether/isohexanes to give 6-bromooxindole (8.2 g, 42%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06265411B1 |
| 出典データセット | uspto-grants-2001_07 |
| ORD ID | ord-f7fae3e4e5694ee78bf254612174d1f3 |
| 出典メモ | uspto-grants-2001_07 |