Dimethyl methylphosphonate → Dimethyl(3-(2-tetrahydropyranyl)oxy-2-oxoheptyl)phosphonate

反応式

[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[O:7][CH:8]([CH2:13][CH2:14][CH2:15][CH3:16])[C:9]([O:11]C)=O.[CH3:17][P:18](=[O:23])([O:21][CH3:22])[O:19][CH3:20]>>[CH3:20][O:19][P:18]([CH2:17][C:9](=[O:11])[CH:8]([O:7][CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6][O:1]1)[CH2:13][CH2:14][CH2:15][CH3:16])(=[O:23])[O:21][CH3:22]

参加物

反応物 2

HCID 12958Dimethyl methylphosphonate

HCID 14323880methyl 2-(tetrahydro-2H-pyran-2-yloxy)hexanoate

生成物 1

HCID 54345769Dimethyl(3-(2-tetrahydropyranyl)oxy-2-oxoheptyl)phosphonate

実験手順

Prepared from methyl 2-(2-tetrahydropyranyl)oxycaproate and dimethyl methylphosphonate according to the known method. (Yield 48%).

出典と根拠

ORDレコード: ord-2ff6402a415a44dda65812d3dbd74962
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06265440B1

反応ノート

読み込み中…