Dimethylamine → Methyl 4-(Dimethylamino)methyl-3-methoxybenzoate

反応式

Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[O:13][CH3:14].[CH3:15][NH:16][CH3:17]>>[CH3:15][N:16]([CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][C:4]=1[O:13][CH3:14])[CH3:17]

参加物

反応物 2

HCID 674Dimethylamine

HCID 2759828Methyl 4-(bromomethyl)-3-methoxybenzoate

生成物 1

HCID 21182956Methyl 4-(Dimethylamino)methyl-3-methoxybenzoate収率 77%

実験手順

The title compound was prepared in 77% yield by essentially following the procedure outlined in Example 37, Part A from methyl 4-bromomethyl-3-methoxybenzoate (see Example 37, Part A) and dimethylamine.

出典と根拠

ORDレコード: ord-944c17a13dd241c1a1fbf46711d9b7b7
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06265575B1

反応ノート

読み込み中…