Dimethylamine → 2-(4-chlorophenoxy)-N,N-dimethylethanamine

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][CH2:10]Br)=[CH:4][CH:3]=1.[CH3:12][NH:13][CH3:14]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:9][CH2:10][N:13]([CH3:14])[CH3:12])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 674Dimethylamine

HCID 748541-(2-Bromoethoxy)-4-chlorobenzene

生成物 1

HCID 52619502-(4-chlorophenoxy)-N,N-dimethylethanamine収率 61%

実験手順

The title compound was prepared in 61% yield (26% SM recovered) by essentially following the procedure outlined in Example 34, Part A from 2-bromoethyl 4-chlorophenyl ether and dimethylamine.

出典と根拠

ORDレコード: ord-d93b0bef1d9447c191f0b4a4eac5178f
出典データセット: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06265575B1

反応ノート

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