Itaconic acid → 4-Methyl hydrogen 2-methylenesuccinate
反応式
[C:1]([OH:9])(=[O:8])[C:2]([CH2:4][C:5]([OH:7])=[O:6])=[CH2:3].[C:10](Cl)(=O)C1C=CC=CC=1>CO>[CH3:10][O:6][C:5]([CH2:4][C:2]([C:1]([OH:9])=[O:8])=[CH2:3])=[O:7]参加物
4
実験手順
To a methanol (100 ml) solution of itaconic acid (100 g), benzoyl chloride (4 ml) was added dropwise under stirring. The reaction solution was stirred at 60-70° C. for 20 minutes and then concentrated under reduced pressure. The resulting solid was recrystallized from a mixed solution of benzene and petroleum ether to obtain 4-methyl itaconate (93 g, melting point: 65-67° C.).
後処理
- stirringThe reaction solution was stirred at 60-70° C. for 20 minutes
- concentrationconcentrated under reduced pressure
- customThe resulting solid was recrystallized from a mixed solution of benzene and petroleum ether
出典と根拠
- ORDレコード
- ord-8b1844667bde477aa74942da04cd3b90
- 出典データセット
- uspto-grants-2001_07
- 特許番号
- US06268511B1
反応ノート
読み込み中…