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Acetonitrile → 4-(Trifluoromethoxy)benzoyl azide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetonitrile | HCID 6342 | — |
| 反応物 | 18-Crown-6 | HCID 28557 | — |
| 反応物 | Sodium Azide | HCID 33557 | — |
| 反応物 | Benzoyl fluoride, 4-(trifluoromethoxy)- | HCID 67612 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 4-(Trifluoromethoxy)benzoyl azide | HCID 13281314 | — |
反応手順
A mixture of 5 grams (24 mmol) of 4-(trifluoromethoxy)benzoyl fluoride, 1.87 grams (29 mmol) of sodium azide, 0.2 grams of 18-Crown-6 ether, and 20 ml. of acetonitrile was stirred at room temperature for two hours under an atmosphere of dry nitrogen. The reaction mixture was diluted with diethyl ether, filtered and concentrated under reduced pressure, with a bath temperature of 40° C., to give the title compound as a turbid oil. IR showed adsorptions at 2280, 2240 and 1695 cm-1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04431667 |
| 出典データセット | uspto-grants-1984_02 |
| ORD ID | ord-f79fc335e7344fa0a0035b33648b6dbd |
| 出典メモ | uspto-grants-1984_02 |