Dichloromethane → HCID 70426821、化合物

反応式

C[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][CH2:10][C:11]([NH:13][NH2:14])=[O:12].[C:15](OC(=O)C)(=[O:17])[CH3:16].Cl[CH2:23]Cl>>[CH3:23][CH:10]([NH:9][C:3]1[C:4]([CH3:8])=[CH:5][CH:6]=[CH:7][CH:2]=1)[C:11]([NH:13][NH:14][C:15](=[O:17])[CH3:16])=[O:12]

参加物

反応物 3

HCID 6344Dichloromethane

HCID 7918Acetic Anhydride

HCID 302666STK017412

生成物 1

HCID 70426821HCID 70426821、化合物

反応条件

温度: 25 °C

実験手順

To a stirred solution of 19.9 g (0.103 mol) alpha-(2,6-dimethylphenylamino)acethydrazide in 350 ml dichloromethane was added quickly 11.3 g (0.103 mol) acetic anhydride. A mild exotherm ensued. After being stirred at about 25° C. for about 16 hours, the reaction mixture was filtered to give 8.9 g of 1-(2,6-dimethylphenylaminoacetyl)-2-acetyl hydrazine, m.p. 148°-150° C.

後処理

filtrationthe reaction mixture was filtered

出典と根拠

ORDレコード: ord-070b6b5da43f446f982203b4b8d74e02
出典データセット: uspto-grants-1981_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04243408

反応ノート

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