Methylamine → 3-(Methylamino)-1lambda6-thiolane-1,1-dione hydrochloride

HRID 1389024

反応式

HRID 1389024 の反応式
CN.[ClH:3].[S:4]1(=[O:11])(=[O:10])[CH2:8][CH2:7][CH:6]([NH2:9])[CH2:5]1.S1(=O)(=O)CC=C[CH2:13]1>>[ClH:3].[CH3:13][NH:9][CH:6]1[CH2:7][CH2:8][S:4](=[O:11])(=[O:10])[CH2:5]1

参加物

4

反応物 3

HCID 6329MethylamineHCID 64983-SulfoleneHCID 27952013-Aminotetrahydrothiopene 1,1-dioxide hydrochloride

生成物 1

HCID 27708173-(Methylamino)-1lambda6-thiolane-1,1-dione hydrochloride収率 82.2%

実験手順

The procedure of Example 1 was repeated substituting 50 percent aqueous monomethylamine (174 ml.) for the ammonium hydroxide of Example 1. Sixty-four and seven-tenths grams of a white crystalline solid was obtained for a yield of 82.2 percent of theory based upon the 2,5-dihydrothiophene 1,1-dioxide. The solid sublimes over 180° C. and melts between 205° and 210° C.

後処理

  1. customSixty-four and seven-tenths grams of a white crystalline solid was obtained for a yield of 82.2 percent of theory
  2. customover 180° C.
  3. custommelts between 205° and 210° C.

出典と根拠

ORDレコード
ord-50ba1ef4505f4260a70041457de95328
出典データセット
uspto-grants-1981_01
特許番号
US04243524

関連ノート

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