化工社化工社 化学情報印刷レポート · 研究参考用
Bifonazole → HCID 178521215、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bifonazole | HCID 2378 | — |
| 反応物 | Phenacyl bromide | HCID 6259 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | HCID 178521215 | HCID 178521215 | 82.5% |
反応手順
15.1 g (0.05 mol) of 1-[α-(4-biphenylyl)-benzyl]-imidazole and 10 g (0.05 mol) of ω-bromoacetophenone are suspended in 500 ml of acetonitrile. After stirring for 15 hours at room temperature, the resulting clear solution is concentrated to about 50 ml. The crystals which hereupon separate out are filtered off and dried. 21 g (82.5% of theory) of 1-[α-(4-biphenylyl)-benzyl]-3-phenacylimidazolium bromide of melting point 210° C. (with decomposition) are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04243670 |
| 出典データセット | uspto-grants-1981_01 |
| ORD ID | ord-49fe7d9561af495989e10a8de316869c |
| 出典メモ | uspto-grants-1981_01 |