Hydrochloric Acid → 2,3,5-Trichloropyridine
反応式
[ClH:1].[Cl:2][CH:3]([CH2:6][C:7]([Cl:11])(Cl)[CH:8]=O)[C:4]#[N:5]>CN(C)C=O>[Cl:1][C:8]1[C:7]([Cl:11])=[CH:6][C:3]([Cl:2])=[CH:4][N:5]=1参加物
4
実験手順
Hydrogen chloride is passed into a solution of 25.0 g (0.125 mol) of 2,4,4-trichloro-4-formylbutyronitrile in 50 mml of N,N-dimethylformamide at a rate such that the temperature of the reaction mixture does not exceed 120° C. After completion of the reaction, the reaction mixture is poured into ice water. The beige-coloured precipitate is filtered off and dried. There is obtained 15.1 g (66% of theory) of 2,3,5-trichloropyridine, m.p. 48°-50° C.
後処理
- customdoes not exceed 120° C
- customAfter completion of the reaction
- filtrationThe beige-coloured precipitate is filtered off
- customdried
出典と根拠
- ORDレコード
- ord-ad586ac676814a4fb26d43aafef2631c
- 出典データセット
- uspto-grants-1981_01
- 特許番号
- US04245098
反応ノート
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