Quinoline → cis-2,5-Dimethyl-3-hexene-2,5-diol

HRID 1389569

反応式

HRID 1389569 の反応式
C(=O)([O-])[O-].[Ca+2].N1C2C(=CC=CC=2)C=CC=1.[CH3:16][C:17]([OH:25])([C:19]#[C:20][C:21]([CH3:24])([OH:23])[CH3:22])[CH3:18].[H][H]>CO>[CH3:16][C:17]([OH:25])(/[CH:19]=[CH:20]\[C:21]([CH3:24])([OH:23])[CH3:22])[CH3:18]

参加物

6

反応物 4

HCID 7047QuinolineHCID 88832,5-Dimethyl-3-hexyne-2,5-diolHCID 10112Calcium CarbonateHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 11126394cis-2,5-Dimethyl-3-hexene-2,5-diol収率 99.4%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

1.6 g of 5% palladized calcium carbonate and 0.6 g of quinoline were added to a solution of 24 g of 2,5-dimethyl-hex-3-yne-2,5-diol [Ray et al, Am. Soc., Vol. 74 (1952), p. 1247] in 200 ml of methanol and the mixture was stirred with hydrogen until hydrogen absorption ceased. The catalyst was removed by filtration and the filtrate was evaporated to dryness under reduced pressure to obtain 24.2 g of cis 2,5-dimethyl-hex-3-ene-2,5-diol melting at 64° C. which was used as is for the next step.

後処理

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-468207694ddc487b9aaf2731a4d3a4d5
出典データセット
uspto-grants-1981_01
特許番号
US04245112

関連ノート

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