7-Amino-3-azidomethyl-3-cephem-4-carboxylic acid → 7-[3-(2-Thienylsulfinyl)butyramido]-3-azidomethyl-3-cephem-4-carboxylic acid

HRID 1389590ノート

反応式

HRID 1389590 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([CH:8]([CH3:13])[CH2:9][C:10]([OH:12])=O)=[O:7].[NH2:14][CH:15]1[C:29](=[O:30])[N:17]2[C:18]([C:26]([OH:28])=[O:27])=[C:19]([CH2:22][N:23]=[N+:24]=[N-:25])[CH2:20][S:21][C@H:16]12>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([CH:8]([CH3:13])[CH2:9][C:10]([NH:14][CH:15]1[C:29](=[O:30])[N:17]2[C:18]([C:26]([OH:28])=[O:27])=[C:19]([CH2:22][N:23]=[N+:24]=[N-:25])[CH2:20][S:21][C@H:16]12)=[O:12])=[O:7]

参加物

3

反応物 2

HCID 128022197-Amino-3-azidomethyl-3-cephem-4-carboxylic acidHCID 202971543-(2-Thienylsulfinyl)butyric acid

生成物 1

HCID 1317120327-[3-(2-Thienylsulfinyl)butyramido]-3-azidomethyl-3-cephem-4-carboxylic acid

実験手順

436 mg. of 3-(2-thienylsulfinyl)butyric acid and 7-amino-3-azidomethyl-3-cephem-4-carboxylic acid were reacted in the same manner as described in Example 28 and 292 mg. of 7-[3-(2-thienylsulfinyl)butyramido]-3-azidomethyl-3-cephem-4-carboxylic acid were obtained.

出典と根拠

ORDレコード
ord-f9b9e7f90fb34370a30bd393f5c3f45b
出典データセット
uspto-grants-1981_01
特許番号
US04245107

反応ノート

読み込み中…