化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → N-Formyl-4-bromomethylpiperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-(Bromomethyl)piperidine hydrobromide | HCID 13503217 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Methyl formate | HCID 7865 | — |
| 生成物 | N-Formyl-4-bromomethylpiperidine | HCID 19812293 | — |
反応手順
To a solution of 4-bromomethylpiperidin hydrobromide (12.8 g, 0.05 mole) in water (5 ml), methyl formate (25 ml) and potassium carbonate (10 g) were added and the mixture stirred for 20 hours. The solvent was decanted, and the residue was extracted with two 25 ml portions of ether. The combined organic phases were washed with water, dried and evaporated to give (A) as a colourless oil. The IR spectrum (chloroform) showed a strong band at 1650 cm-1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04246262 |
| 出典データセット | uspto-grants-1981_01 |
| ORD ID | ord-54a83d9fc37c4287bd1bcfc5f8fc4ffa |
| 出典メモ | uspto-grants-1981_01 |