化工社化工社 化学情報印刷レポート · 研究参考用
Acetone → 1,1-Dimethylhydroxymethylbis(2-cyanoethyl)-phosphine oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | N,N,N',N',N''-Pentamethylguanidine | HCID 139457 | — |
| 反応物 | HCID 178511210 | HCID 178511210 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | 1,1-Dimethylhydroxymethylbis(2-cyanoethyl)-phosphine oxide | HCID 88766983 | 88% |
反応手順
To a mixture of 0.1 mol of bis(2-cyanoethyl)phosphine oxide and 0.1 mol of acetone was added 1.0 gram of either triethyl amine or pentamethyl guanidine. The mixture was heated for 2 hours at steam bath temperatures. The resulting solid was filtered and recrystallized from acetone to give an 88% yield of product, m.p. 124°-125° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04247447 |
| 出典データセット | uspto-grants-1981_01 |
| ORD ID | ord-842a394f7c5a4c3cb602647f6bf0e708 |
| 出典メモ | uspto-grants-1981_01 |