N-(2-Hydroxyethyl)ethylenediamine → Mitoxantrone Impurity 2

HRID 1390210

反応式

HRID 1390210 の反応式
[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH2:7].[CH2:8]1[C:22](=O)[C:21]2[C:12](=[C:13]([OH:27])[C:14]3[C:19]([C:20]=2[OH:24])=[C:18](O)[CH:17]=[CH:16][C:15]=3O)[C:10](=[O:11])[CH2:9]1>>[OH:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:15]1[C:14]2[C:13](=[O:27])[C:12]3[C:21](=[C:22]([NH:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2][OH:1])[CH:8]=[CH:9][C:10]=3[OH:11])[C:20](=[O:24])[C:19]=2[C:18]([NH:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2][OH:1])=[CH:17][CH:16]=1

参加物

3

反応物 2

HCID 8112N-(2-Hydroxyethyl)ethylenediamineHCID 664859,10-Anthracenedione, 2,3-dihydro-1,4,5,8-tetrahydroxy-

生成物 1

HCID 22748598Mitoxantrone Impurity 2

実験手順

The reaction between 2-(2-hydroxyethylamino)ethylamine and leuco-1,4,5,8-tetrahydroxyanthraquinone is carried out as in Example 1 to give the title compound.

出典と根拠

ORDレコード
ord-e915004d62dd4f3381b5b89bf83c8938
出典データセット
uspto-grants-1979_02
特許番号
US04138415

関連ノート

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