Ethanol → HCID 23335847、化合物

HRID 1390223ノート

反応式

HRID 1390223 の反応式
Cl[S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:4])=[O:3].[CH2:18]([OH:20])[CH3:19].C(N(CC)CC)C.O>C(OCC)(=O)C>[CH2:18]([O:20][S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:3])=[O:4])[CH3:19]

参加物

6

反応物 4

HCID 702EthanolHCID 962WaterHCID 8471TriethylamineHCID 23335839alpha-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid

生成物 1

HCID 23335847HCID 23335847、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

α-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid (5 mmole) is added to 30 ml of ethyl acetate. To this mixture is added 5 mmole of ethanol in 10 ml of ethyl acetate which contains 10 mmole of triethylamine. The mixture is stirred at room temperature for about 1 hour and 50 ml of water is added. The pH is adjusted to about 6.5 and the layers separated. The organic layer is dried over magnesium sulfate, filtered and evaporated to give ethoxysulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid.

後処理

  1. customthe layers separated
  2. dry with materialThe organic layer is dried over magnesium sulfate
  3. filtrationfiltered
  4. customevaporated

出典と根拠

ORDレコード
ord-d772c42358164a16995fa82176d9fb7a
出典データセット
uspto-grants-1979_02
特許番号
US04138397

反応ノート

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