Boron trifluoride etherate → 3-(4-Chlorophenyl)-2,3-dihydro-1H-indole

HRID 1390268ノート

反応式

HRID 1390268 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][CH:9]=2)=[CH:4][CH:3]=1.B(F)(F)F.CCOCC>[Zn].C(O)(=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[NH:10][CH2:9]2)=[CH:6][CH:7]=1

参加物

5

反応物 2

HCID 8000Boron trifluoride etherateHCID 153224793-(4-Chlorophenyl)-1H-indole

生成物 1

HCID 537323163-(4-Chlorophenyl)-2,3-dihydro-1H-indole

試薬・触媒・溶媒 2

HCID 23994Zinc触媒HCID 176Acetic Acid溶媒

実験手順

Using the same procedure as detailed in Example 1 3.5 g of 3-p-chlorophenylindole, 35 ml of glacial acetic acid, 7 ml of boron trifluoride etherate and 7 g of zinc dust were reacted together and the product worked up as in Example 1. In this way 1.5 g of the desired 3-p-chlorophenylindoline was obtained as a yellow oil.

後処理

  1. customwere reacted together

出典と根拠

ORDレコード
ord-824c9da88642485a9f01eb1ef4e3af0e
出典データセット
uspto-grants-1979_02
特許番号
US04138494

反応ノート

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