Dimethylamine → 5-Acetyl-2-dimethylaminobenzenesulphonamide
反応式
[C:1]([C:4]1[CH:5]=[CH:6][C:7](Cl)=[C:8]([S:10]([NH2:13])(=[O:12])=[O:11])[CH:9]=1)(=[O:3])[CH3:2].[CH3:15][NH:16][CH3:17]>C(O)C>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([N:16]([CH3:17])[CH3:15])=[C:8]([S:10]([NH2:13])(=[O:12])=[O:11])[CH:9]=1)(=[O:3])[CH3:2]参加物
4
実験手順
A mixture of 5-acetyl-2-chloro-benzenesulphonamide (0.5 g) in ethanol (10 ml) and dimethylamine in ethanol (33%, 5 ml) was heated in a closed vessel on a steam bath for 16 hours. The solvents were removed under reduced pressure and the residue crystallised from ethanol to give the product 0.31 g, m.p. 184°-185°.
後処理
- temperaturewas heated in a closed vessel on a steam bath for 16 hours
- customThe solvents were removed under reduced pressure
- customthe residue crystallised from ethanol
出典と根拠
- ORDレコード
- ord-1549e093f701489f816a05493178400c
- 出典データセット
- uspto-grants-1979_02
- 特許番号
- US04140713
反応ノート
読み込み中…