2,5-Dimethylphenol → HCID 54001442、化合物

反応式

[CH3:1][C:2]1[CH:3]=[C:4]([OH:9])[C:5](C)=[CH:6][CH:7]=1.[Cl-].[Al+3].[Cl-].[Cl-].Cl[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C1(C(C2C=CC=CC=2)CC(Cl)=O)C=CC=CC=1>[OH:9][C:4]1[CH:3]=[C:2]([CH3:1])[C:7]([C:2]([CH3:1])([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:3][C:4]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:9])=[CH:6][CH:5]=1

参加物

実験手順

Twenty-four and four-tenths grams of 3,6-dimethylphenol and 26.6 grams of aluminum chloride are dissolved in 250 mls chlorobenzene and 48.9 grams of 3,3-diphenylpropionic acid chloride, dissolved in 150 mls chlorobenzene, are added while stirring. The stirring is continued for several days at 100° C. The chlorobenzene is evaporated in vacuo, the residue is mixed with ice and ether and washed several times with water. After drying with sodium sulfate, the ether is evaporated. Fifteen and one-tenth grams of 4-hydroxy-3,6-dimethyl-β,β-diphenylpropiophenone are obtained.