1-Methyl-5-phenyl-1H-pyrazole-4-carboxylic acid → Methyl-5-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-yl-isopropyl-amide

HRID 1393047ノート

反応式

HRID 1393047 の反応式
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[NH:11][CH:12]([CH3:14])[CH3:13])[CH2:8]2.[CH3:15][N:16]1[C:20]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[C:19]([C:27](O)=[O:28])[CH:18]=[N:17]1>>[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[N:11]([CH:12]([CH3:14])[CH3:13])[C:27]([C:19]1[CH:18]=[N:17][N:16]([CH3:15])[C:20]=1[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)=[O:28])[CH2:8]2

参加物

3

反応物 2

HCID 27954741-Methyl-5-phenyl-1H-pyrazole-4-carboxylic acidHCID 43406547Adamantan-2-yl-isopropyl-amine2 回

生成物 1

HCID 58724612Methyl-5-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-yl-isopropyl-amide

実験手順

Methyl-5-phenyl-1H-pyrazole-4-carboxylic acid adamantan-2-yl-isopropyl-amide is prepared from adamantan-2-yl-isopropyl-amine (of intermediate 3) and 1-methyl-5-phenyl-1H-pyrazole-4-carboxylic acid (Maybridge plc, Cornwall, UK) according to general procedure C.

出典と根拠

ORDレコード
ord-14a7373cdb0a40bd94bd2cb6db69d6bb
出典データセット
uspto-grants-2008_03
特許番号
US07345058B2

反応ノート

読み込み中…