Hydrochloric Acid → 3-[N-(2-Cyclohexylethyl)amino]propionamide hydrochloride
反応式
[ClH:1].C(OC([N:9]([CH2:18][CH2:19][C:20]([NH2:22])=[O:21])[CH2:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=O)(C)(C)C>O1CCOCC1>[ClH:1].[CH:12]1([CH2:11][CH2:10][NH:9][CH2:18][CH2:19][C:20]([NH2:22])=[O:21])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1参加物
4
実験手順
Next, a 4 N solution of hydrogen chloride in 1,4-dioxane (3.1 ml) was added to 3-[N-(t-Butoxycarbonyl)-N-(2-cyclohexylethyl)amino]propionamide (0.37 g, 1.2 mmol), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, diisopropyl ether was added to the resulting solid, and the solid was filtered off to give 0.30 g (quantitatively) of the titled compound as colorless crystals.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure, diisopropyl ether
- additionwas added to the resulting solid
- filtrationthe solid was filtered off
出典と根拠
- ORDレコード
- ord-35adba935166477d97010516cc525c09
- 出典データセット
- uspto-grants-2008_03
- 特許番号
- US07345064B2
反応ノート
読み込み中…