関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 3,5-Dimethylaniline | HCID 7949 | — |
| 反応物 | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 3-(3,5-Dimethylphenyl)amino-4-nitrophenol | HCID 21938154 | — |
反応手順
5.4 g of 3-fluoro-4-nitrophenol and 4.3 ml of 3,5-dimethylaniline were mixed and stirred for 6 hours at 120° C. After cooling, it was taken up in ethyl acetate and water and extracted three times with 1N aqueous hydrochloric acid. The combined aqueous phases were extracted three times with ethyl acetate. The combined organic phases were dried on sodium sulfate, concentrated by evaporation in a vacuum, and the residue was crystallized.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07345075B2 |
|---|
| 出典データセット | uspto-grants-2008_03 |
|---|
| ORD ID | ord-bcea5b27711246bcb25a415921eaedd6 |
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| 出典メモ | uspto-grants-2008_03 |
|---|
