Sodium Dithionite → 2-(4-Aminophenylamino)ethanesulfonamide

HRID 1393834ノート

反応式

HRID 1393834 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][S:13]([NH2:16])(=[O:15])=[O:14])=[CH:6][CH:5]=1)([O-])=O.S(S([O-])=O)([O-])=O.[Na+].[Na+]>C(O)C>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][CH2:11][CH2:12][S:13]([NH2:16])(=[O:14])=[O:15])=[CH:8][CH:9]=1

参加物

4

反応物 2

HCID 24489Sodium DithioniteHCID 231044412-(4-Nitrophenylamino)ethanesulfonamide

生成物 1

HCID 231044432-(4-Aminophenylamino)ethanesulfonamide収率 79.7%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1 g of 2-(4-nitrophenylamino)ethanesulfonamide (12) was suspended in 10 mL of ethanol. At room temperature, the suspension was poured onto a reductive solution of sodium hydrosulfite (8 g)—1N sodium hydroxide (30 mL). After decolorization, a precipitate formed. 0.7 g of crude product was isolated by suction-filtering and reslurrying in water.

後処理

  1. customAfter decolorization, a precipitate formed

出典と根拠

ORDレコード
ord-2535bde458e24411a61dd72c00e52b04
出典データセット
uspto-grants-2008_03
特許番号
US07347879B2

反応ノート

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