3-Fluorophenylboronic acid → 5-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
反応式
Br[C:2]1[CH:3]=[C:4]2[CH2:10][C:9](=[O:11])[NH:8][C:5]2=[N:6][CH:7]=1.[F:12][C:13]1[CH:14]=[C:15](B(O)O)[CH:16]=[CH:17][CH:18]=1>>[F:12][C:13]1[CH:18]=[C:17]([C:2]2[CH:3]=[C:4]3[CH2:10][C:9](=[O:11])[NH:8][C:5]3=[N:6][CH:7]=2)[CH:16]=[CH:15][CH:14]=1参加物
3
実験手順
The title compound was prepared in 32% yield according to the procedure described in Example 2, starting from 5-bromo-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one (prepared according to the procedure described in WO2003082868, Page 33) and 3-fluoro-phenyl boronic acid. 1H NMR is the same as the one reported in WO2003082868, page 34.
後処理
- customprepared
出典と根拠
- ORDレコード
- ord-381618189eea48a79589aaa20fb785d6
- 出典データセット
- uspto-grants-2008_03
- 特許番号
- US07348432B2
反応ノート
読み込み中…