Potassium Carbonate → HCID 20340108、化合物
反応式
[CH3:1][O:2][C:3]([NH:5][C:6]1[CH:7]=[C:8]([O:12][C:13](Cl)=[O:14])[CH:9]=[CH:10][CH:11]=1)=[O:4].C(=O)([O-])[O-].[K+].[K+].Cl.[Cl:23][CH2:24][CH2:25][NH:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>O>[CH3:1][O:2][C:3]([NH:5][C:6]1[CH:7]=[C:8]([O:12][C:13](=[O:14])[N:26]([CH2:25][CH2:24][Cl:23])[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[CH:9]=[CH:10][CH:11]=1)=[O:4]参加物
5
実験手順
A solution of 22.9 g of chloroformic acid-3-methoxycarbonylaminophenylester in 50 ml acetic acid ester is added dropwise together with a solution of 30.5 g potassium carbonate in 150 ml water at a temperature of 10° to 15° C. into a solution of 23 g N-(2-chloroethyl)-aniline hydrochloride in 50 ml water and 50 ml acetic acid ester. During the addition the solutions are stirred. The stirring is then continued for 30 minutes at 15° C. whereupon the organic phase is separated, diluted with about 100 ml acetic acid ester and washed at 0° C. successively with dilute sodium hydroxide, water, dilute hydrochloric acid and again water. After drying on magnesium sulfate the mass is concentrated by evaporation under a reduced pressure. The residue obtained is at first oily but soon crystallizes throughout and is then recrystallized from acetic acid ester/pentane.