Diethyl Oxalate → HCID 67133792、化合物
反応式
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][C:5]([NH2:12])=[C:4]([NH2:13])[CH:3]=1.[C:14](OCC)(=[O:20])[C:15](OCC)=[O:16]>>[CH3:1][C:2]1[CH:3]=[C:4]2[C:5]([NH:12][C:14](=[O:20])[C:15](=[O:16])[NH:13]2)=[CH:6][C:7]=1[C:8]([O:10][CH3:11])=[O:9]参加物
3
反応条件
- 温度
- 145 °C
実験手順
A mixture of 3.98 g of methyl 4,5-diamino-2-methyl benzoate and 40 mL of diethyl oxalate was stirred at 145° C. for 3 hours. After cooling to room temperature, the solid was collected by filtration, washed with diethyl ether, and dried under reduced pressure to obtain 4.75 g of methyl 7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate.
後処理
- temperatureAfter cooling to room temperature
- filtrationthe solid was collected by filtration
- washwashed with diethyl ether
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-92c27bd6dd8d4b0fa81edd4957b549c1
- 出典データセット
- uspto-grants-2014_12
- 特許番号
- US08901126B2
反応ノート
読み込み中…