3-(4-Chlorophenyl)-1-(3-fluorophenyl)propan-1-one → HCID 131732156、化合物

反応式

ClC1C=CC(CCC(C2C=CC=C(F)C=2)=O)=CC=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([CH2:26][CH2:27]/[C:28](/[C:35]2[CH:40]=[CH:39][CH:38]=[C:37]([F:41])[CH:36]=2)=[CH:29]/[C:30]([O:32][CH2:33][CH3:34])=[O:31])=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([CH2:26][CH2:27]/[C:28](/[C:35]2[CH:40]=[CH:39][CH:38]=[C:37]([F:41])[CH:36]=2)=[CH:29]\[C:30]([O:32][CH2:33][CH3:34])=[O:31])=[CH:24][CH:25]=1

参加物

反応物 2

HCID 247260833-(4-Chlorophenyl)-1-(3-fluorophenyl)propan-1-one

HCID 67379723HCID 67379723、化合物

生成物 1

HCID 131732156HCID 131732156、化合物

実験手順

By a procedure similar to that of example 1.85.3, starting from 3-(4-chlorophenyl)-1-(3-fluorophenyl)propan-1-one, (Z)-ethyl 5-(4-chlorophenyl)-3-(3-fluorophenyl)pent-2-enoate and (E)-ethyl 5-(4-chlorophenyl)-3-(3-fluorophenyl)pent-2-enoate were obtained as colourless oils.

出典と根拠

ORDレコード: ord-69f43dc2ca454af2a635a9538fc408e3
出典データセット: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08912186B2

反応ノート

読み込み中…