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HRID 1404167作成日:2026年10月27日

Phenylboronic Acid → 3-(2,3-Dimethyl-4-{[1-phenyl-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}phenyl)propan-1-ol

https://huagongshe.com/reaction/1404167

反応式

関与物質

役割名称HCID仕込み量
反応物Phenylboronic AcidHCID 66827—
反応物Ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoateHCID 58566491—
反応物methyl 3-(trifluoromethyl)-1H-pyrrole-2-carboxylateHCID 90405535—
生成物3-(2,3-Dimethyl-4-{[1-phenyl-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}phenyl)propan-1-olHCID 90406462—

反応手順

The title compound was prepared by (a) reacting the product prepared in Step B of Example 1 and phenylboronic acid according to the procedure described in Example 1, Step C, (b) then reacting the resulting product according to the procedure in Example 1, Step D, (c) then reacting the resulting product with ethyl 3-(2,3-dimethyl-4-hydroxyphenyl)propanoate according to the procedure in Example 1, Step E, and Example 2.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08912227B1
出典データセットuspto-grants-2014_12
ORD IDord-c3769d36aa444669a08c50cd86a55d3a
出典メモuspto-grants-2014_12