化工社化工社 化学情報印刷レポート · 研究参考用
2,3,5-Trifluorobenzyl alcohol → 4-{4-Fluoro-2-[(2,3,5-trifluorobenzyl)oxy]phenyl}-N-{3-[(methylsulfonyl)methyl]-phenyl}-1,3,5-triazin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,3,5-Trifluorobenzyl alcohol | HCID 2777030 | — |
| 反応物 | 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine | HCID 70976524 | — |
| 生成物 | 4-{4-Fluoro-2-[(2,3,5-trifluorobenzyl)oxy]phenyl}-N-{3-[(methylsulfonyl)methyl]-phenyl}-1,3,5-triazin-2-amine | HCID 66576056 | — |
反応手順
Starting with 4-(2,4-difluorophenyl)-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine (70 mg; 0.184 mmol), intermediate 42.1, and 2,3,5-trifluorobenzyl alcohol (119 mg; 0.736 mmol), example 84 was prepared analogously to the procedure for the preparation of example 42.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08916557B2 |
| 出典データセット | uspto-grants-2014_12 |
| ORD ID | ord-c140f3d4ab1b492d98feddd62f9b30b4 |
| 出典メモ | uspto-grants-2014_12 |