化工社化工社 化学情報印刷レポート · 研究参考用
Trimethylsilyldiazomethane → Methyl 3-bromo-5-(hydroxymethyl)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 反応物 | 3-Bromo-5-(hydroxymethyl)benzoic acid | HCID 8167127 | — |
| 溶媒 | Benzene methanol | HCID 21927730 | — |
| 生成物 | Methyl 3-bromo-5-(hydroxymethyl)benzoate | HCID 11356988 | — |
反応手順
To 3-bromo-5-(hydroxymethyl)benzoic acid (7.0 g, 30 mmol) in 20% methanol/benzene (100 mL) is added trimethylsilyldiazomethane (2M in hexanes), and the reaction is stirred 16 h. The reaction is concentrated under reduced pressure to afford the title compound. ESI MS m/z 244.0 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07727997B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-a362f1bc326742dc8cca9713458fb263 |
| 出典メモ | uspto-grants-2010_06 |