4-[(2-Amino-6-chloropyrimidin-4-yl)amino]benzonitrile → 4-[(2-Amino-6-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]amino}-pyrimidin-4-yl)amino]benzonitrile

HRID 141097

反応式

[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2.[NH2:19][c:20]1[n:21][c:22]([Cl:35])[cH:23][c:24]([NH:26][c:27]2[cH:28][cH:29][c:30]([C:31]#[N:32])[cH:33][cH:34]2)[n:25]1>>[F:1][c:2]1[cH:3][c:4]([NH:5][c:22]2[n:21][c:20]([NH2:19])[n:25][c:24]([NH:26][c:27]3[cH:28][cH:29][c:30]([C:31]#[N:32])[cH:33][cH:34]3)[cH:23]2)[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2