N,N-Diethylethylenediamine → HCID 70549843、化合物
反応式
[CH2:1]([N:3]([CH2:6][CH2:7][NH2:8])[CH2:4][CH3:5])[CH3:2].[O:9]1[C:14]2[CH:15]=[CH:16][CH:17]=[C:18]([C:19]([Cl:21])=[O:20])[C:13]=2[O:12][CH2:11][CH2:10]1>CC(C)=O>[ClH:21].[CH2:1]([N:3]([CH2:6][CH2:7][NH:8][C:19]([C:18]1[C:13]2[O:12][CH2:11][CH2:10][O:9][C:14]=2[CH:15]=[CH:16][CH:17]=1)=[O:20])[CH2:4][CH3:5])[CH3:2]参加物
4
反応条件
- 温度
- 0 °C
実験手順
21 g of diethylaminoethylamine and 85 ml of acetone were introduced into a balloon flask provided with an agitator and a thermometer. The mixture was cooled to 0° C. and then 36 g of 1,4-benzodioxane-5-carbonyl chloride were added. The crystals formed at ambient temperature were dried off, washed with acetone, dried and purified by recrystallization from isopropyl alcohol. 36.5 g of N-(diethylaminoethyl)-1,4-benzodioxane-5-carboxamide hydrochloride were obtained (M.P.: 120° C.; yield: 64%).