Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene
反応式
[Cl:1][C:2]1[C:3]([CH2:8][S:9][CH2:10][CH2:11][NH2:12])=[N:4][CH:5]=[CH:6][CH:7]=1.[C:13]([CH:15]=[C:16](OCC)[NH:17][C:18]#[C:19][CH3:20])#[N:14].C(N)C#C.C(C=C(OCC)OCC)#N>>[C:13]([CH:15]=[C:16]([NH:17][CH2:18][C:19]#[CH:20])[NH:12][CH2:11][CH2:10][S:9][CH2:8][C:3]1[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][N:4]=1)#[N:14]参加物
5
実験手順
When 2-[(3-chloro-2-pyridyl)methylthio]ethylamine is reacted with 1-cyano-2-ethoxy-2-propynylaminoethylene [prepared from propargylamine and 1-cyano-2,2-bis(ethoxy)ethylene, which is itself prepared according to the procedure described in J. Am. Chem. Soc., 71, 47 (1949)], the title product is produced.
後処理
- customprepared
出典と根拠
- ORDレコード
- ord-a6975d6e40114ebb8b63e4ace4143ae8
- 出典データセット
- uspto-grants-1981_02
- 特許番号
- US04250316
反応ノート
読み込み中…