Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene

HRID 1413563ノート

反応式

HRID 1413563 の反応式
Cl[C:2]1[C:3](CSCCN)=[N:4]C=C[CH:7]=1.C(C=C(OC)OC)#N.[C:21]([CH:23]=[C:24](OC)[NH:25][CH2:26][CH2:27][S:28][CH2:29][C:30]1[C:35]([Cl:36])=[CH:34][CH:33]=[CH:32][N:31]=1)#[N:22].C(N)C#C>>[C:21]([CH:23]=[C:24]([NH:4][CH2:3][C:2]#[CH:7])[NH:25][CH2:26][CH2:27][S:28][CH2:29][C:30]1[C:35]([Cl:36])=[CH:34][CH:33]=[CH:32][N:31]=1)#[N:22]

参加物

5

実験手順

When 2-[(3-chloro-2-pyridyl)methylthio]ethylamine is reacted with 1-cyano-2,2-bis(methoxy)ethylene and the resultant 1-cyano-2-methoxy-2-{2-[(3-chloro-2-pyridyl)methylthio]ethylamino}ethylene is reacted with propargylamine according to the general procedure of Example 1 Step B the title compound is produced.

出典と根拠

ORDレコード
ord-cf312665a3b24e5dbcef9a3ac8012139
出典データセット
uspto-grants-1981_02
特許番号
US04250316

反応ノート

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