Isobutylamine → 2-(3-chlorophenoxy)N-isobutylnicotinamide
反応式
[CH2:1]([NH2:5])[CH:2]([CH3:4])[CH3:3].[Cl:6][C:7]1[CH:8]=[C:9]([CH:20]=[CH:21][CH:22]=1)[O:10][C:11]1[N:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13](Cl)=[O:14]>C1(C)C=CC=CC=1>[Cl:6][C:7]1[CH:8]=[C:9]([CH:20]=[CH:21][CH:22]=1)[O:10][C:11]1[N:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([NH:5][CH2:1][CH:2]([CH3:4])[CH3:3])=[O:14]参加物
4
実験手順
In the same manner as in Example 1(c) 1.4 grams (0.02 mole) isobutylamine and 2.7 grams (0.01 mole) of the acyl chloride produced in step (b) were combined in 50 milliliters toluene to yield 2.8 grams (92.1% of theoretical yield) of the desired product, m.p. 86°-87° C. The structure was confirmed by mass spectrometry.
後処理
- customto yield
出典と根拠
- ORDレコード
- ord-5ca4ef4a074943e2a50da4c8c1a9315b
- 出典データセット
- uspto-grants-1981_02
- 特許番号
- US04251263
反応ノート
読み込み中…