Ethyl vinyl ether → 2-Ethoxy-4-phenyl-3,4-dihydro-2h-pyran

反応式

[CH:1]1[CH:6]=[CH:5][C:4](/[CH:7]=[CH:8]/[CH:9]=[O:10])=[CH:3][CH:2]=1.[CH:11]([O:13][CH2:14][CH3:15])=[CH2:12]>>[CH2:11]([O:13][CH:14]1[CH2:15][CH:7]([C:4]2[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=2)[CH:8]=[CH:9][O:10]1)[CH3:12]

参加物

反応物 2

HCID 8023Ethyl vinyl ether

HCID 637511Cinnamaldehyde

生成物 1

HCID 2801772-Ethoxy-4-phenyl-3,4-dihydro-2h-pyran

実験手順

treating cinnamic aldehyde with ethyl vinyl ether to afford 2-ethoxy-4-phenyl-3,4-dihydro-2H-pyran, hydrogenating the resulting product to afford 3-cyclohexylpentane-1,5-diol and finally heating the above diol in the presence of a dehydrogenation catalyst to afford 3-cyclohexyl-pentanolide; or

出典と根拠

ORDレコード: ord-948df3d4cf5b47b6af07726b82caa3fb
出典データセット: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04251398

反応ノート

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