Potassium Carbonate → HCID 21487992、化合物

HRID 1414611ノート

反応式

HRID 1414611 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[CH:15]=2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37]Cl)[CH3:34]>CC(C)=O>[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:15]=[C:16]([CH3:21])[CH:17]=[C:18]([CH3:20])[CH:19]=2)=[CH:6][CH:7]=1)[CH3:34]

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 13364Diethylaminoethyl chlorideHCID 21487920HCID 21487920、化合物

生成物 1

HCID 21487992HCID 21487992、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

2-p-Hydroxyphenyl-3-(3',5'-dimethylbenzoyl)benzofuran (5.25 g., 15.3 mmol.) was dissolved in 200 ml. of dry acetone and 10.5 g. (0.076 mol.) of potassium carbonate and 2.10 g. (15.3 mmol.) of 2-diethylaminoethyl chloride were added. The reaction mixture was refluxed for three hours, then it was cooled and filtered. The filtrate was concentrated at reduced pressure to give the title compound as an oil.

後処理

  1. temperatureThe reaction mixture was refluxed for three hours
  2. temperatureit was cooled
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated at reduced pressure

出典と根拠

ORDレコード
ord-f3021689b5424ac09203357e407fc367
出典データセット
uspto-grants-1977_01
特許番号
US04001426

反応ノート

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