3,5-Dimethylbenzoyl Chloride → HCID 21487949、化合物

反応式

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[S:11][CH:10]=2)=[CH:5][CH:4]=1.[CH3:18][C:19]1[CH:20]=[C:21]([CH:25]=[C:26]([CH3:28])[CH:27]=1)[C:22](Cl)=[O:23]>>[CH3:18][C:19]1[CH:20]=[C:21]([CH:25]=[C:26]([CH3:28])[CH:27]=1)[C:22]([C:10]1[S:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:9]=1[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)=[O:23]

参加物

反応物 2

HCID 810883,5-Dimethylbenzoyl Chloride

HCID 3358921HCID 3358921、化合物

生成物 1

HCID 21487949HCID 21487949、化合物

実験手順

3-p-Methoxyphenylbenzothiophene is acylated with 3,5-dimethylbenzoyl chloride as previously described to give 2-(3',5'-dimethylbenzoyl)-3-p-methoxyphenylbenzothiophene. Demethylation with pyridine hydrochloride followed by reaction of the hydroxy compound thus formed with diethylaminoethyl chloride as described above gives the title compound.

出典と根拠

ORDレコード: ord-f9c7700da8c342feb81bf2fe565de0c2
出典データセット: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04001426

反応ノート

読み込み中…

参加物